The association between hypertension, obesity and hyperlipidemia is well established. Undoubtedly one of the most important risk factors for hypertension is obesity and all overweight and obese persons are at risk for hypertension, high blood cholesterol, type 2 diabetes, and coronary heart disease.A cluster of metabolic factors that increase the risk for atherosclerotic cardiovascular disease is called "metabolic syndrome". Afflicted individuals may by defined by the presence of three of the following five characteristics: central obesity, hypertriglyceridemia, low high-density lipoprotein levels,hypertension, and either impaired fasting glucose or type 2 diabetes. World is currently facing the silent epidemic of metabolic syndrome. Efficay of Safoof-e-muhazzil,a classical unani antiobesity formulation based on the observations in clinical trial raises its scope of utility beyond obesity And perhaps may pave the way for development of a single formulation which will take care of all co-morbidities of metabolic syndrome which is gaining epidemic proportions world over.