High Quality Content by WIKIPEDIA articles! Quantification of Margins and Uncertainty (QMU) is a decision-support methodology for complex technical decisions. QMU focuses on the identification, characterization, and analysis of performance thresholds and their associated margins for engineering systems that are evaluated under conditions of uncertainty, particularly when portions of those results are generated using computational modeling and simulation. QMU has traditionally been applied to complex systems where comprehensive experimental test data is not readily available and cannot be easily generated for either end-to-end system execution or for specific subsystems of interest. Examples of systems where QMU has been applied include nuclear weapons performance, qualification, and stockpile assessment. QMU focuses on characterizing in detail the various sources of uncertainty that exist in a model, thus allowing the uncertainty in the system response output variables to be well...