There has been an upsurge in the number of coronary artery disease (CAD) cases worldwide, of late now, and CAD, as such, looms large among the killer diseases of the world. In the current scenario, India stands as the CAD capital of the world. It is postulated that more than half of the worldwide cardiovascular risk burden will be borne by India and the Indian sub-continent in the next decade [Gupta R et al, 2008]. There is a significant difference in the prevalence of CAD with respect to gender, age, ethnicity and cardiovascular disease has been emerging as a major health burden in the developing world [Reddy KS et al, 1998]. Also, the risk factors for ischemic heart disease as well as the acute coronary syndrome are on the rise in people of Indian origin [Gupta M et al, 2006; Jafar TH et al, 2005].With the increase in number of cases of coronary artery disease, interest has generated among researchers to look for the newer and modifiable risk factors for CAD. Whereas, the modification of risk factors would help prevent the very onset of CAD as well as decrease the incidence thereof, a new set of prognostic markers are being discussed worldwide.